health department to issue guidance about doxycycline as an infection-prevention measure. Nevertheless, the San Francisco Department of Public Health in October became the first U.S. And widespread use of doxycycline as a preventive measure could contribute to mutations that make bacteria impervious to the drug, as has happened with antibiotics before. Some research has found it ineffective in heterosexual women. Philip Andrew Chan, who is consulting with the CDC on the doxycycline recommendations.Īmong them: The drug can cause side effects like stomach problems and rashes after sun exposure. “We do need new approaches, new innovations” to help bring sexually transmitted infections under control, said Dr. The study was led by researchers at the University of California, San Francisco and built on a similar French study that saw promise in the idea. Those who took the pills were about 90% less likely to get chlamydia, about 80% less likely to get syphilis, and more than 50% less likely to get gonorrhea compared with people who did not take the pills after sex, the researchers found. In the study, about 500 gay men, bisexual men and transgender women in Seattle and San Francisco with previous STD infections took one doxycycline pill within 72 hours of unprotected sex. A study published last week in the New England Journal of Medicine showed its potential to prevent sexually transmitted infections. The drug is already used to treat a range of infections. Leandro Mena, director of the agency's STD prevention division. The Centers for Disease Control and Prevention is drafting recommendations for using it as a kind of morning-after pill for preventing STDs, said Dr.
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